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Glycobiology at the Crossroads: Sunday, November 8 (Day 1)
8:00 am – 6:00 pm
Registration Open
8:30 am – 11:30 am
Workshop: Glyco in Biotechnology (extra fee required; continental breakfast included)
Parastoo Azadi, Associate Director, Complex Carbohydrate Research Center 9:00 am – 12:00 pm
Board Meeting
12:00 pm – 5:45 pm
Glycopalooza: Trainee & New PI Mixer (extra fee required, lunch included)
6:00 pm – 6:30 pm
OPENING SESSION
Karin Hoffmeister, SFG President 6:30 pm – 7:00 pm
Awardee Lecture: Karl Meyer Award
Hudson Freeze, Sanford Children's Health Research Center 7:00 pm – 7:30 pm
Awardee Lecture: Glycobiology Significant Achievement Award
Stacy Malaker, Yale University 7:30 pm – 9:00 pm
Welcome & Networking Reception
8:00 pm - 9:00 pm
Fireside Discussion (Sign-up Required)
Pascal Gagneux, University of California San Diego Theme: Quo Vadis? Monday, November 9 (Day 2)
6:45 am – 7:30 am
Glyco Wellness Class: Laughter Yoga (Sign-up Required)
7:00 am – 8:00 am
Continental Breakfast
7:30 am – 5:30 pm
Registration
7:30 am – 4:00 pm
Exhibits Open
Technologies, Systems Glycobiology and Neuroscience
8:00 am – 9:05 am
SESSION 1: Capturing the Glycome: From Structure to Function
Chair: Daniel Kolarich, Griffith University, Australia
8:00 am – 8:15 am
Welcome Remarks: Karin Hoffmeister, Versiti
8:15 am – 8:35 am
Keynote Speaker: Daniel Kolarich, Griffith University, Australia
Pending
8:35 am – 8:55 am
Keynote Speaker: Qi Zhang, Emory University
Decoding Glycoproteome Remodeling in Alzheimer’s Disease Brain
8:55 am – 9:00 am
Poster Talk: Huilin Hao, University of Georgia
Profiling of O-fucose proteome of POFUT1 and POFUT2 using 6-alkynyl fucose 9:00 am – 9:05 am
Poster Talk: Yi-Chang Liu, Glycogenetics, Inc.
Streamlining the use of human lectins for immunological assays and immunostaining 9:10 am – 10:20 am
SESSION 2: How Carbohydrate Synthesis Informs Glycan Structural Models
Chair: Debra Mohnen, University of Georgia
9:10 am – 9:30 am
Keynote Speaker: Debra Mohnen, University of Georgia
Informing plant cell wall glycan structural models through studies of pectin synthesis - Arabidopsis GALACTURONOSYLTRANSFERASE (GAUT) 1 as a prototype for the “Multiple Pectin Heteroglycan Model” of cell wall architecture
9:30 am – 9:50 am
Keynote Speaker: Clifford Okoye, University of Georgia
Initiation and Elongation of Pectic Homogalacturonan Synthesis on Rhamnogalacturonan by Glycosyltransferases GAUT13 and GAUT14
9:50 am – 9:55 am
Poster Talk: Pradeepa Jayawardhane, University of Georgia
Exploring the Biosynthesis of Pectic Rhamnogalacturonan I (RG-I) and its Biological Function in Arabidopsis Embryo Development 9:55 am – 10:15 am
Keynote Speaker: Jochen Zimmer, University of Virginia School of Medicine
Insights into the formation and architecture of polysaccharide fibrils
10:15 am – 10:20 am
Poster Talk: Teresa Beamon, University of Alabama at Birmingham
Desmoglein 2 (DSG2) ST6GAL1 Mediated Sialylation Modulates Desmosome Ultrastructure and Strength in CRC 10:20 am – 10:35 am
Morning Break
10:35 am – 11:45 am
SESSION 3: Emerging Voices in Glycobiology: New Tools, Developmental Biology, and Therapeutic Frontiers
Chair: Ramon Sun, University of Florida
10:35 am – 10:55 am
Keynote Speaker: Sizun Jiang, Beth Israel Deaconess / Harvard Medical School
Don't Panic! A Hitchhiker's Guide to Reading the Glyco-centric Immune System In Situ
10:55 am – 11:15 am
Keynote Speaker: Kim Alonge, University of Washington
Dynamic remodeling of hypothalamic extracellular matrices in metabolic diseases
11:15 am – 11:20 am
Poster Talk: Isaac Nathoo, New York University Langone Health
Dietary Fructose Directly Fuels N-Linked Glycosylation to Promote Colorectal Cancer Progression 11:20 am – 11:40 am
Keynote Speaker: Sean Bendall, Stanford University
Bottom-Up Organization of Single Cell Human Systems
11:40 am – 11:45 am
Poster Talk: Ujala Bashir, University of Gothenburg, Sweden
Beyond the Secretory Pathway: Oncogenic Signalling Regulates Extended Glycosylation in the Nucleus 11:45 am – 1:30 pm
Lunch Provided (advance lunch group selection required)
Please note: Lunch will be served in two seating groups. Optional sessions have been scheduled during both lunch periods, giving attendees an opportunity to participate either before or after their scheduled lunch.
Teaching Glyco Workshop: Interactive Teaching Resources from BioF:GREAT
Two 45-minute sessions | Same content offered at both times
Interested in bringing glycobiology into your teaching? Explore BioF:GREAT’s evidence-based teaching resources through an interactive case study and discuss ways to adapt them for undergraduate, professional, and other educational settings.
1:30 pm – 2:40 pm
SESSION 4: Glycobioinformatics & Systems Glycobiology
Chair: Morihisa Fujita, Gifu University
1:30 pm – 1:50 pm
Keynote Speaker: Morihisa Fujita, Gifu University
From Systems-Level Glycan Pathway Analysis to Cellular Engineering of Human Milk Oligosaccharide Biosynthesis
1:50 pm – 1:55 pm
Poster Talk: Neil Patel, University of Georgia
A non-canonical EZH2/TRIM28 epigenetic axis drives heparan sulfate remodeling and melanoma metastasis 1:55 pm – 2:15 pm
Keynote Speaker: Yoshiki Narimatsu, University of Copenhagen
Engineering Cell-Based Platforms to Decode Glycan Recognition and Host-Microbe Interactions
2:15 pm – 2:20 pm
Poster Talk: José Pires, University of Copenhagen
Gastric epithelial differentiation shapes mucin expression, glycosylation and mucus properties in human organoid monolayers 2:20 pm – 2:40 pm
Keynote Speaker: Kiyoko Aoki-Kinoshita, Soka University
Federated Data, a National Glycome Atlas, and Agentic AI: Layers of Infrastructure for Systems Glycobiology
2:45 pm – 3:55 pm
SESSION 5: Neuroglycobiology: Brain Glycans in Development and Disease
Chair: Robbie Mealer, University of North Carolina at Chapel Hill
2:45 pm – 3:05 pm
Keynote Speaker: Robbie Mealer, University of North Carolina at Chapel Hill
Protein O-GalNAc glycosylation in brain development and disease
3:05 pm – 3:10 pm
Poster Talk: Caden Summers, Texas A&M University
Collaboration and antagonism between receptor protein tyrosine phosphatases and protein O-mannosyltransferases POMT1/2 in the Drosophila nervous system 3:10 pm – 3:30 pm
Keynote Speaker: Boyoung Lee, Institute for Basic Science of Korea
O-Glycan Sialylation as a Novel Molecular Mechanism Underlying Depressive-Like Behaviors
3:30 pm – 3:35 pm
Poster Talk: Jeffery Fairley, University of Georgia
Investigating the Downstream Effects of O-GlcNAc Transferase (OGT) in X- Linked Intellectual Disability 3:35 pm – 3:55 pm
Keynote Speaker: Sophia Shi, The Rowland Institute at Harvard
Glycocalyx Regulation of the Blood–Brain Barrier
4:00 pm – 5:30 pm
POSTER SESSION I: Theme: Mechanisms & Technology
5:30 pm – 6:00 pm
Awardee Lecture: President’s Innovator Award
Ajit Varki, and Nissi Varki, University of California San Diego 6:00 pm – 7:00 pm
Fireside Discussion: Pascal Gagneux, University of California San Diego
Theme: Quo Vadis? 7:00 pm
Dinner on Your Own
Tuesday, November 10 (Day 3)
6:45 am – 7:30 am
3K Walk-for-Glyco (Sign-up Required)
7:00 am – 8:00 am
Continental Breakfast
7:30 am – 5:30 pm
Registration
7:30 am – 5:30 pm
Exhibits Open
Glycans in Development, Evolution, and Precision Medicine
8:00 am – 9:10 am
SESSION 6: Glycans in Evolution and Reproduction: Can Life Evolve Without Sugar Codes
Chair: Pascal Gagneux, University of California San Diego
8:00 am – 8:20 am
Keynote Speaker: Pascal Gagneux, University of California San Diego
Patterning of Cellular Life via Sugar Coates?
8:20 am – 8:25 am
Poster Talk: Iain Wilson, Universität für Bodenkultur
A tale of two insects: N-glycomics of the fruit fly and the silkworm 8:25 am – 8:45 am
Keynote Speaker: Anne Harduin-Lepers, Université de Lille, France
Diversity and Evolution of the Vertebrate Sialyltransferase Repertoire
8:45 am – 8:50 am
Poster Talk: Ratmir Derda, University of Alberta
Biological recognition of mirror image glycans 8:50 am – 9:10 am
Keynote Speaker: Petar Pajic, Yale University
Ancient MUC1 repeat expansion links mucus barrier defense to pleiotropic tradeoffs
9:15 am – 10:25 am
SESSION 7: From Glycocode to Precision Oncology
Chair: Hans Wandall, University of Copenhagen/Denmark
9:15 am – 9:35 am
Keynote Speaker: Hans Wandall, University of Copenhagen/Denmark | Celso Reis, University of Porto / Portugal
Targeting glycosylation for precision oncology
9:35 am – 9:55 am
Keynote Speaker: Robert Manguso, Broad Institute
CD43 is a glyco-immune checkpoint for anti-leukemic immunity
9:55 am – 10:00 am
Poster Talk: Sangwoo Park, Harvard Medical School and Massachusetts General Hospital
KLK5-secreting CAR-T cells remodel the tumor glycocalyx to enhance antitumor activity in solid tumors 10:00 am – 10:20 am
Keynote Speaker: Vered Padler-Karavani, Broad Institute
Targeting glycans in health and disease
10:20 am – 10:25 am
Poster Talk: Mathieu Decloquement, University of Alberta
Deciphering Siglec ligands in cancer to improve immunotherapy 10:25 am – 10:45 am
Beverage Break
10:45 am – 11:55 am
SESSION 8: Glycans in Blood Cell Function
Chair: Heyu Ni, University of Toronto/Canada
10:45 am – 11:05 am
Keynote Speaker: Heyu Ni, University of Toronto/Canada
Platelet desialylation and immune response: Novel mechanisms of immune thrombocytopenia and therapeutic targets
11:05 am – 11:25 am
Keynote Speaker: Dianne van Der Wal, University of Sydney
Of mice of men; The feedback of glycans in platelet activation and extracellular vesicle release-Implications for Transfusion.
11:25 am – 11:30 am
Poster Talk: Natalia Weich, Versiti Blood Research Institute
Nascent pre-platelets and B4GALT1 glycosylation contribute to 5-FU–induced bone marrow recovery 11:30 am – 11:50 am
Keynote Speaker: Alejandro Roisman, Versiti Translational Glycomics Center
Glycosylation Orchestrates Megakaryocytic Fate of Hematopoietic Stem Cells via Wnt-MUC13 Signaling
11:50 am – 11:55 am
Poster Talk: Adam Knier, Medical College of Wisconsin
O-GlcNAcylation Regulates ACTH Secretion in Corticotroph Adenoma 12:00 pm – 1:45 pm
Lunch Provided (advance lunch group selection required)
Please note: Lunch will be served in two seating groups. Optional sessions have been scheduled during both lunch periods, giving attendees an opportunity to participate either before or after their scheduled lunch.
12:00 pm – 12:45 pm Glycopalooza: Trainee Poster Blitz
A fast-paced session where trainees deliver brief, high-impact 5-minute overviews of their research 1:00 pm – 1:45 pm Glycopalooza: PI Lab Pitches
A rapid-fire session where principal investigators showcase their research programs, scientific interests, and opportunities for collaboration or employment 1:45 pm – 2:55 pm
SESSION 9: Mechanobiology of Glycans: Molecular Mechanics to Cell Function
Chair: Jennifer Curtis, Georgia Tech
1:45 pm – 2:05 pm
Keynote Speaker: Khalid Salaita, Emory University
How the Mucin Glycocalyx Physically Rewires Adhesion Mechanotransduction
2:05 pm – 2:10 pm
Poster Talk: Sonal Mahajan, Sanford Burnham Prebys
COG4-Associated Golgi Dysfunction Impairs Proteoglycan-Rich Matrix Assembly in Patient iPSC-Derived Cartilage Organoids from Saul-Wilson Syndrome 2:10 pm – 2:30 pm
Keynote Speaker: Ralf Richter, University of Leeds/United Kingdom
Glycosaminoglycans in cell adhesion and trafficking
2:30 pm – 2:35 pm
Poster Talk: Petar Hristov, Harvard University
Intact and single-molecule analysis of heparan sulfate 2:35 pm – 2:55 pm
Keynote Speaker: Jennifer Curtis, Georgia Tech
The Glycocalyx Sweet Spot: Hyaluronan Homeostasis and the Control of Cell Adhesion
2:55 pm – 4:05 pm
SESSION 10: Antibody Glycosylation: How Sugars Control the Immune System
Chair: Eric Sundberg, Emory University School of Medicine
2:55 pm – 3:15 pm
Keynote Speaker: Jeffrey Ravetch, Rockefeller University
IgG Fc glycosylation modulates innate and adaptive immunity
3:15 pm – 3:35 pm
Keynote Speaker: Taia T. Wang, Stanford University
Antibody Glycosylation as a Regulator of Immune Function
3:35 pm – 3:40 pm
Poster Talk: Rajindra Aryal, BIDMC, Harvard Medical School
IgM present in Circulating Immune Complexes from IgA Nephropathy Patients Directly Binds to the Tn Antigen Within IgA1 and Is Mitogenic to Mesangial Cells 3:40 pm – 4:00 pm
Keynote Speaker: Diego Sastre, Emory University
Engineered endoglycosidases selectively target afucosylated IgG and suppress pathogenic antibody effector functions
4:05 pm – 4:20 pm
Beverage Break
4:20 pm – 5:30 pm
SESSION 11: Microbe-Host Interactions via Glycans
Chair: Sean Stowell, Harvard Medical School
4:20 pm – 4:40 pm
Keynote Speaker: Connie Arthur, Harvard Medical School
Regulation of Naturally Occurring Anti-ABO Antibody Formation
4:40 pm – 4:45 pm
Poster Talk: Aaron Petrey, University of Utah
The C-type Lectin and Hyaluronan Receptor Layilin Regulates IL10 Signaling in Macrophages 4:45 pm – 5:05 pm
Keynote Speaker: Fu-Tong Liu, USC
Intracellular galectins in host-microbe interaction through binding cytosolically exposed host or microbial glycans
5:05 pm – 5:25 pm
Keynote Speaker: Richard Cummings, Harvard/Beth Israel
Anti-Glycan Immune Responses in Microbial Infections: Implications for Health and Autoimmunity
5:25 pm – 5:30 pm
Poster Talk: Daniel Propheter, The University of Texas Southwestern Medical Center
Adiponectin recognizes bacterial lipopolysaccharide glycans to protect against enteric and systemic infection 5:30 pm – 7:00 pm
POSTER SESSION II - Theme: Translational & Clinical
7:30 pm – 10:00 pm
Banquet Dinner (additional fee required)
Wednesday, November 11 (Day 4)
6:45 am – 7:30 am
Glyco Wellness Class: Meditation (Sign-up Required)
7:00 am – 8:00 am
Continental Breakfast
7:30 am – 11:00 am
Registration
7:30 am – 11:00 am
Exhibits Open
Reading the Glycome: New Frontiers in Biosynthesis and Reproduction
8:00 am – 9:10 am
SESSION 12: Unexpected events in glycoconjugate biosynthesis
Chair: Jennifer Kohler, UT Southwestern Medical Center
8:00 am – 8:20 am
Keynote Speaker: Yazuhiko Kizuka, Gifu University/Japan
Lectin domain-mediated regulation of glycosyltransferases for N-glycan branching and LacdiNAc biosynthesis
8:20 am – 8:40 am
Keynote Speaker: Manxiao Ma, Stanford University
Regulated N-glycosylation controls chaperone function and receptor trafficking
8:40 am – 8:45 am
Poster Talk: Ke Wang, University of Utah
Programmable Glycocalyx Engineering Reveals Glycodomain Control of MUC1 Signaling and Dimerization 8:45 am – 9:05 am
Keynote Speaker: Daniel Bojar, Gothenburg University/Sweden
Dirt Is Matter Out Of Place: Glycobiology Goes Nuclear
9:05 am – 9:10 am
Poster Talk: Dahai Ding, University of Georgia
Red Blood Cell Surface Engineering for Influenza Hemagglutination Using Synthetic Sialylated N-Glycans 9:10 am – 10:20 am
SESSION 13: Glycobiology in Women's Health: The Sugar Code of Reproductions
Chair: Stephanie Olivier-Van Stichelen, Medical College of Wisconsin
9:10 am – 9:30 am
Keynote Speaker: Stephanie Olivier-Van Stichelen, Medical College of Wisconsin
The Role of Intracellular Glycosylation in Placental Metabolic Adaptation During Pregnancy
9:30 am – 9:50 am
Keynote Speaker: Aubrey Converse, Northwestern University
Age-associated disruption of the hyaluronan matrix impairs cumulus-oocyte complex expansion and ovulation
9:50 am – 9:55 am
Poster Talk: Sridevi Krishnan, University of Arizona
Glycogene-Specific Polygenic Risk Score Predicts Glycemia in Type 2 Diabetes And Is Modified By Nutrient Exposure 9:55 am – 10:15 am
Keynote Speaker: Virginia Tajadura-Ortega, Imperial College London
Host glycan and mucin interactions with the vaginal microbiota associated with preterm birth 10:15 am – 10:20 am
Poster Talk: Olivia Plisko, University of North Carolina at Chapel Hill
Human milk oligosaccharide degradation by microbial sialidases in the breastfed infant gut microbiome 10:20 am – 10:30 am
Morning Break
10:30 am – 11:00 am
Awardee Lecture: Rosalind Kornfeld
11:00 am – 11:30 am
Trainee/Poster Awards
11:30 am – 12:30 pm
Business Meeting & Closing
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