Mass Spectrometry Scientist

Requisition ID #: 34470
Job Category: Research
Employment Type: Full Time
Experience Level: Experienced (non-manager)
City, State: Milwaukee, WI
Work Location: Translational and Biomedical Research Center Department: Cancer Center
Education: Doctorate Degree 

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Position Description: 

The Medical College of Wisconsin (MCW) brings a synergy between the best medical education, research and patient care. Tomorrow’s discoveries happen right here alongside the very people who bring those lessons to our students. Every bit of knowledge, and every advancement, provides our students with an unprecedented, collaborative learning environment, and helps improve the vitality and care of our communities. In the role of a Mass Spectrometry Scientist, you will be working in Cancer Center.

Purpose:

The Mass Spectrometry Core (MSC), Translational Metabolomics Shared Resource (TraM SR) is a newly established core at the Medical College of Wisconsin Cancer Center (MCWCC). This position seeks an exceptional and motivated PhD level research scientist to join our Mass Spectrometry Core at the MCWCC. This position will work with the TraM SR MSC team:

  1. to develop analytical methods and run samples to support research projects at the MCW.
  2. to maintenance and operate LC-MS and imaging MALDI MS instrument.
  3. to assist the Director of the MSC when needed.

Primary Functions:

  • Plan and complete the most complex procedures: participate in discovery projects.

  • Follow Standard Operational Procedures (SOPs) to consistently perform sample preparation procedures for lipidomics, metabolomics, proteomics, glycomics, and biologics characterization analysis.
  • Independently follow SOPs to conduct experiments in a timely manner, including upfront sample extraction, MS sample preparation, sample purification/fractionation and LC-MS operations.

  •  Effectively document fine details/incidents of experiments performed.
  • Optimize sample preparation workflow of biomolecules including lipids, small molecules, metabolites, complex glycans and proteins and lead research projects.
  • Build and develop MS workflow for lipidomics, metabolomics, glycomics and proteomics. 
  • Maintain and operate LC-MS and imaging MALDI-MS instruments; including maintenance of one or more instruments at the same time.
  • Routinely report, update, and communicate with the Director of MSC.
  • Review research methodologies; plan, develop and compose protocols for implementation, assessment, testing, cost effectiveness, and quality.
  • Plan and perform MS analyses using advanced techniques; determine and review findings with investigators and recommend experimental design and modifications in analytical protocols.
  • Prepare scientific reports, outcome findings and scientific manuscripts. Assist in outcome interpretation and composition of the results sections of manuscripts and reports.

  • Participate in meetings with principal investigator and research staff and evaluate/interpret the validity of data, develop methodologies, evaluate lab procedures.
  • Train students, residents and post-doctoral fellows in specific research protocols; develop training materials.
  • Develop, implement and maintain a computerized record system for reporting results. 

Knowledge/Skills/Abilities:

Knowledge of biology, chemistry, biochemistry, analytical chemistry, documentation, and records management. Solid understanding and knowledge of general chemistry and separation science. Mass Spectrometry experience. Experience with proteomic, lipidomics, metabolomics, or glycomics. Experience with LC-MS, Orbitrap, and MALDI-MS. Experience with MS software is preferred. Hands-on experience in HPLC, UHPLC and mass spectrometry. Experienced with handling various samples such as cell lysate, tissues, or any biological fluids. Proficiency on technical operating systems. Proven problem solving and troubleshooting abilities. Effective oral and technical written communication skills. Ability to work in both independent and collaborative environments. Time management and project management skills.

Preferred Schedule: Monday - Friday 8:00am. - 4:30pm.
Position Requirements: Specifications Appropriate experience may be substituted for education on an equivalent basis. 
Minimum Required Education: PhD in a scientific field.
Minimum Required Experience: 4 years.
Preferred Experience: Experience with proteomic, lipidomics, metabolomics, or glycomics. Experience with LCMS, Orbitrap, and MALDI-MSField: Biochemistry, chemistry, analytical chemistry, or related field.

Why MCW?:

  • Outstanding Healthcare Coverage, including but not limited to Health, Vision, and Dental. Along with Flexible Spending options
  • 403B Retirement Package
  • Competitive Vacation and Paid Holidays offered
  • Tuition Reimbursement
  • Paid Parental Leave
  • Pet Insurance
  • On campus Fitness Facility, offering onsite classes.
  • Additional discounted rates on items such as: Select cell phone plans, local fitness facilities, Milwaukee recreation and entertainment etc.

For a full list of positions see: https://www.mcw.edu/departments/human-resources/careers

For a brief overview of our benefits see: https://www.mcw.edu/departments/human-resources/benefits 

Eastern Wisconsin is a vibrant, diverse metropolitan area. MCW is intent on attracting, developing, and retaining a diverse workforce and faculty body that reflects the community we serve. We value diversity of backgrounds, experience, thought, and perspectives to advance excellence in science and medicine. MCW is a welcoming campus community with a strong culture of collaboration, partnership, and engagement with our surrounding community. For more information, please visit our institutional website at https://www.mcw.edu/departments/office-of-diversity-and-inclusion.

MCW as an Equal Opportunity Employer and Commitment to Non-Discrimination. The Medical College of Wisconsin (MCW) is an Equal Opportunity Employer. We are committed to fostering a diverse community of outstanding faculty, staff, and students, as well as ensuring equal educational opportunity, employment, and access to services, programs, and activities, without regard to an individual's race, color, national origin, religion, age, disability, sex, gender identity/expression, sexual orientation, marital status, pregnancy, predisposing genetic characteristic, or military status. Employees, students, applicants or other members of the MCW community (including but not limited to vendors, visitors, and guests) may not be subjected to harassment that is prohibited by law or treated adversely or retaliated against based upon a protected characteristic.

Posted September 25, 2024